var xhr = new XMLHttpRequest();
xhr.open('POST', 'someURLForTheUpload', true); //my url had the ID of the item that the blob corresponded to
xhr.responseType = 'Blob';
xhr.setRequestHeader("x-csrf-token",csrf); //if you are doing CSRF stuff
xhr.onload = function(e) { /*irrelevant code*/ };
xhr.send(blob);