Михаил

class MyModel(models.Model):

    m2mfield = ManyToManyField(OtherModel)

    @staticmethod
    def met(sender, instance, action, reverse, model, pk_set, **kwargs):
        if action == 'pre_add':
            # here you can modify things, for instance
            pk_set.intersection_update([1,2,3]) 
            # only save relations to objects 1, 2 and 3, ignoring the others
        elif action == 'post_add':
            print pk_set
            # should contain at most 1, 2 and 3

m2m_changed.connect(receiver=MyModel.met, sender=MyModel.m2mfield.through)