<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8">
<link rel="stylesheet" href="style.css">
<title>Document</title>
</head>
<body>
<div class="wrapper">
<div class="images">
<div class="box2"><img src="http://dummyimage.com/497x246/555/fff.png" /></div>
<div class="box"><img src="http://dummyimage.com/246x246/555/fff.png" /></div>
<div class="box"><img src="http://dummyimage.com/246x246/555/fff.png" /></div>
<div class="clear"></div>
<div class="box"><img src="http://dummyimage.com/246x246/555/fff.png" /></div>
<div class="box"><img src="http://dummyimage.com/246x246/555/fff.png" /></div>
<div class="box2"><img src="http://dummyimage.com/497x246/555/fff.png" /></div>
<div class="clear"></div>
<div class="box2"><img src="http://dummyimage.com/497x246/555/fff.png" /></div>
<div class="box"><img src="http://dummyimage.com/246x246/555/fff.png" /></div>
<div class="box"><img src="http://dummyimage.com/246x246/555/fff.png" /></div>
<div class="clear"></div>
<div class="box"><img src="http://dummyimage.com/246x246/555/fff.png" /></div>
<div class="box"><img src="http://dummyimage.com/246x246/555/fff.png" /></div>
<div class="box2"><img src="http://dummyimage.com/497x246/555/fff.png" /></div>
<div class="clear"></div>
</div>
</div>
</body>
</html>
.wrapper{
position: static;
width: 100%;
margin: auto;
}
.images{
width: 95%;
max-width: 1000px;
}
.box{
width: 25%;
float: left;
padding: 1px;
box-sizing: border-box;
}
.box2{
width: 50%;
float: left;
padding: 1px;
box-sizing: border-box;
}
.box img{
width:100%;
max-width: 246px;
height: auto;
}
.box2 img{
width:100%;
max-width: 497px;
height: auto;
}
.clear {
clear: both;
}